Replication Data for: Spatial metabolomics identifies LPC(18:0) and LPA(18:1) in advanced atheroma with translation to plasma for cardiovascular risk estimation

DOI
  • MALDI mass spectrometry imaging data (FT-ICR, 40 µm lateral resolution) of 9 human and 22 animal model (LDLR-deficient) atherosclerotic tissue samples.
  • LC-MS data of LPC(18:0) and LPA(18:1) in human plasma from subjects with elective coronary artery bypass grafting (CABG, CV-risk group, n=27) and a control group (n=27).
  • High-spatial resolution MALDI mass spectrometry imaging data (TOF, 10 µm lateral resolution) of 1 animal model (LDLR-deficient) atherosclerotic tissue sample.
  • High-resolution MALDI-2 mass spectrometry imaging data (TOF, 10 µm lateral resolution) of 1 animal model (LDLR-deficient) atherosclerotic tissue sample for imaging cholesterol and derivative molecules.
  • MS/MS data of LPC(18:0) and LPA(18:1) from tissue

For access to data, user needs to make SRAM account on https://sram.surf.nl/ and request access at Point of Contact (C. Lewis, chris.lewis@maastrichtuniversity.nl, or B. Balluff, b.balluff@maastrichtuniversity.nl)

Identifier
DOI https://doi.org/10.34894/TKBBK4
Related Identifier https://doi.org/10.1161/ATVBAHA.123.320278
Metadata Access https://dataverse.nl/oai?verb=GetRecord&metadataPrefix=oai_datacite&identifier=doi:10.34894/TKBBK4
Provenance
Creator Balluff, B. (ORCID: 0000-0003-0351-240X); Alvarez-Llamas, G. (ORCID: 0000-0002-3313-721X)
Publisher DataverseNL
Contributor Balluff, B.; Lewis, C.
Publication Year 2023
Funding Reference China Scholarship Council No. 201706040068 ; Dutch Province of Limburg LINK program ; European Union PI20/01103 ; European Union IF08/3667-1 ; European Union CP22/00100 ; COST action CA17121-47635 ; Conserjeria de Educacion, Juventud y Deporte de la Comunidad de Madrid 2018-T2/BMD-11561
Rights CC0 1.0; info:eu-repo/semantics/openAccess; http://creativecommons.org/publicdomain/zero/1.0
OpenAccess true
Contact Balluff, B. (Maastricht University); Lewis, C. (Maastricht University)
Representation
Resource Type Mass spectrometry (imaging) data; Dataset
Version 1.1
Discipline Life Sciences; Medicine