With the beamtime requested we plan to employ small-angle neutron scattering (SANS) to study novel nanocolloidal drug carriers prepared using lipids, surfactants and co-surfactants. These can address solubility, stability and bioavailability issues of drugs. SANS will be used to monitor:• Size/thickness of surfactant layer of developed systems.• Orientation/ spatial arrangement of components viz. surfactant, co-surfactant and surfactant supporting agents around the lipid core or in the vesicles.• Existence of other structures viz. micelles, supercooled melts or nanostructured lipid carriers.• Particle aggregation.• Particle-particle interactions.• Mesophase or smectic nature of the systems.Systems are aqueous nanodispersions and D2O will be used for neutron contrast. 25 & 37 ◦C, will be used to study changes and amorphous/crystalline nature.