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The action of membrane lytic compounds on model membranes.
The study of antifungal and antibacterial action is of great interest and there are still many unknowns concerning the action of membrane lytic materials, and the way that... -
Structural Studies on Aggregates Formed by Novel Star-Shaped Oligomeric Surfa...
Oligomeric surfactants, where three or more alkyl chains and headgroups are connected via spacer groups with various geometries, have interesting and potentially important... -
Changes of phospholipid aggregate morphology induced by phospholipase hydrolysis
We propose to look at the interaction of the aggregates two phospholipids form with two phospholipase (PL) enzymes, PLA2 and PLC, which hydrolyse different ester groups in the... -
Solubilisation of Drug Molecules in Nonionic Surfactant Micelles: Structural ...
This proposal aims to understand how the structure of non-ionic surfactant micelles affects the amount of fungicides solubilised. SANS is a technique unique for unravelling the... -
SANS evaluation of novel nanocolloidal drug carriers
With the beamtime requested we plan to employ small-angle neutron scattering (SANS) to study novel nanocolloidal drug carriers prepared using lipids, surfactants and... -
Constructing analogues of Gemini and oligomeric surfactants using polyamines
Gemini or oligomeric surfactants, where two or more alkyl chains and headgroups are connected via spacer groups, have interesting and potentially important properties which make...