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Antibiotic Interactions with models of the Gram negative bacterial outer memb...
This dataset has no description
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Structural Observation of the Self-Assembly Kinetics of Cyclic Peptide Nanotubes
Cyclic peptides with alternating side chain stereochemistry are capable of self-assembling into long nanotubes. The conjugation of polymers to these peptides renders the... -
Electrostatic Interactions between Floating Bilayers and Thiol Coated Interfa...
Bilayers which float below a self-assembled monolayer (SAM) coated solid support represent one of the most advanced membrane mimetics. Recently (RB 1720155) we assessed the... -
A total scattering study of the concentration and temperature dependence of s...
Lithium-ion batteries (LIBs) are ubiquitous in our portable electronics, however they are ill suited for applications where cost or sustainability are of paramount importance,... -
Polymer-Lipid Nanodisc Self-assembly Processes Using Stop Flow
Polymer stabilized lipid nanodiscs offer enormous potential as tools for enabling membrane protein structural studies & biophysics. Polymer stabilized lipid bilayer discs... -
Polymer-Lipid Nanodisc Self-assembly Processes Using Stop Flow
Polymer stabilized lipid nanodiscs offer enormous potential as tools for enabling membrane protein structural studies & biophysics. Polymer stabilized lipid bilayer discs... -
Investigation of cement pore structure evolution in underground repository co...
It is proposed that radioactive waste generated in the Netherlands be buried underground in Boom clay formations. As this will need to be stored for hundreds of thousands of... -
Interaction between Rubisco and SDOBS at an air-water interface
Protein-surfactant interactions at an interface play an important role for broad applications in the chemical, dairy, cosmetic and pharmaceutical industries. Rubisco is the most... -
The origin of the dissolution of cellulose in alkali/urea aqueous solution
Cellulose is produced over tens of billions of tons every year in the world. It is one of the most abundant natural polymer resources. Compared with petroleum-based polymers,... -
Morphology of poly(ethylene-oxide)-ionic liquid mixtures: the role of hydroge...
We propose to explore the morphology of binary mixtures of poly(ethylene oxide), a biomimetic macromolecule, and two different ionic liquids, differing in their hydrogen bonding... -
Ibuprofen containing surfactant monolayers: location and stiochiometry of ibu...
An increasing number of potential drug molecules are extremely water insoluble, limiting their commercialisation as medicines. Solubilisation of drug in surfactant micelles is a... -
Determination of the absorbed amount and location of a hydrophobic drug in su...
Many drugs are both poorly water-soluble (hydrophobic) and lipophilic in nature and are therefore incorporated into surfactant micelles and monolayers. As the incorporation of... -
Optimizing micellar drug solubilisation using surfactant designed with a hydr...
In our recent research at Kings we have shown that significant increases in micellar drug solubilization can be achieved by matching' the hydrophobe of a drug with the... -
Quantifying antibiotic resistance using bacterial model membranes
The Gram negative bacterial outer membrane protects the bacterium from toxins such as antibiotics and is partially responsible for the rapid rise in antibiotic resistance in... -
Polarized neutron reflectormetry study of ultra-thin FeRh films.
FeRh in the CsCl structure is an interesting material with a tunable magnetostructural phase transition close to, or just above room temperature. On heating through the... -
Optimisation of Experimental Conditions for the Study of Anionic Self-Assembl...
We have developed a Self-assembled floating supported membrane sample system comprised of unsaturated phospholipid bilayers held ~1nm from a PEGylated charged alkane thiol SAM... -
Hydration and sweetness of synthetic sweeteners
Recently, the degree of sweetness of natural sugars has been associated and correlated to their hydration shell (strength, orientation and length of their hydrogen bonds with... -
Why are choline arginate / choline lysinate mixtures more effective for the p...
We have recently discovered that certain mixtures of the ionic liquids (ILs) cholinium argininate (Ch[Arg]) and cholinium lysinate (Ch[Lys]) are ~ 20% more efficient for the... -
Solvation structure of sodium ions and hexa-fluorophosphate ions in organic c...
Here we propose to study the local structure of sodium in standard organic carbonate electrolytes for sodium ion batteries. Three different electrolytes are chosen to study; a... -
Surface properties of biogenic polyaminesurfactant mixtures
Polyions and biogenic polyamine are ubiquitous in many important biochemical functions. We propose here to use neutron reflectivity to investigate their potential to induce and...
