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A study of protein adsorption via chelating lipids within a solid supported l...
The crystallisation of membrane proteins is of great interest, not least, to the pharmaceutical industry. We have recently begun a project aiming to investigate the role played... -
Structure of Colloidal Crystals Near a Solid Surface
The structure of colloidal crystals (dispersions of particles that spontaneously order in a regular array) is known to be influenced by solid boundaries. However there are few... -
Polarised Neutron Reflectivity investigation of Fe+ ion irradiated Fe-15at%Cr...
For Fusion energy applications FeCr ferritic martensitic steels are candidate structural materials due to their radiation resistance and good mechanical properties. Thus, the... -
Neutron reflectometry from surface of liquid 3He/4He film on silicon wafer
A superfluid helium film can host a variety of exotic quantum phenomena, such as the topological BerezinskiiKosterlitzThouless transition, Rollins film flow and Third sound.... -
Membrane-stacking properties of myelin proteins
Myelin is the multilamellar structure that ensheaths axons and accelerates nervous impulses in the nervous system. The fine structure of myelin remains to be further... -
Defects in the Core Oligosaccharide in Gram Negative Bacterial Outer Membrane...
The outer membrane of Gram negative bacterial is an effective barrier for many harmful agents. We have been developing and testing advanced models of the Gram negative bacterial... -
Surfactant and Polymer Adsorption on Pyrite Thin Films
Pyrite (FeS2) is a hydrophobic mineral surface, i.e. of a type thus far inaccessible to the types of aqueous adsorption experiments suitable for study by reflectometry (NR), but... -
Understanding the true biological function of Plant Non Specific Lipid Transf...
Non specific lipid transfer proteins are a family of basic, cysteine rich proteins found in a wide range of plant species. The biotechnological role of these proteins in beer... -
Dependence of spin-diffusion transparency and spin-orbit torques on interface...
One of the main challenges in spintronics is to provide a link between magnetic elements and conventional electronic circuits. For the switching of a magnetic memory-element an... -
Neutron reflection study of effects of non-ionic alkyl ethoxylates on model w...
We propose to use NR to study the structural features of the model wheat wax films formulated from the known main components of long chain primary alcohols and an ester. By... -
Molecular architecture of monolayers formed by novel sterol-modified phosphol...
A family of sterol-modified glycerophospholipids (SML) have been synthesized in which the sn-1 or sn-2 position is covalently attached to cholesterol and the alternative... -
Organisation of Outer membrane protein F at the air/liquid interface
Crystallisation of membrane proteins as a precursor to high resolution structural studies is a significant research bottleneck. We are investigating alternative methods to... -
Conformational analysis of subtilin / lipid II binary antibiotic/target membr...
Antibiotic resistance is pathogenic bacteria is a major clinical problem. Resistance to all antibiotiotic classes, currentl yin clinical use, has been reported. By contrast, the... -
The Kinetics of Self-Exchange of a Protein at Solid/Liquid interfaces
The formation of a protein corona occurs on all surfaces exposed to biological systems and understanding of how this corona forms is vital for many aspects of medicine and for... -
Planar bilayer formation on novel cationic surface suitable for membrane prot...
Membrane receptor proteins (MRPs) which are thought to represent the majority of drug targets are challenging to study as their structure and function is dependent on being... -
Search for antiferromagnetic coupling in ferromagnetic oxide LSMO-LCMO multil...
La0.7Ca0.3MnO3 (LCMO) and La0.7Sr0.3MnO3 (LSMO) are two oxide ferromagnetic materials. They will be grown on single crystal SrTiO3 substrate. This allows a highly textured... -
Liquid-liquid immiscibility and glass transitions in aqueous solutions
The microscopic structure of a dilute solution of LiCl in water is determined at different thermodynamic states in both the liquid and glassy phases. This solution exhibits... -
The interaction of Plant Defensins with Model Lipid Membranes : Understanding...
Plants do not have the sophisticated immunoglobulin immune systems of vertibrates, instead they posses a series of stimuli based responses which defend against pathogentic... -
Specular Reflectivity and Off-specular scattering from artificial magnetic do...
The study investigates artificially designed in-plane magnetic domain patterns by polarised neutron reflectometry and off-specular scattering. Stripe domains with in-plane... -
Combining polarised neutrons and resonant x-rays to understand temperature-de...
Despite being a well-known phenomenon, the mechanism by which platinum gains a magnetic moment by proximity to a ferromagnetic (FM) thin film remains unknown. We aim to...