The crystallisation of membrane proteins is of great interest, not least, to the pharmaceutical industry. We have recently begun a project aiming to investigate the role played by surfaces in the nucleation and growth of protein crystals. The first step of this process is to study the growth of two-dimentional protein crystals on a solid supported lipid bilayer, prepared according to well established procedures. In this proposal we aim to characterise the adsorption of a protein as it binds to a chelating lipid within a solid supported lipid layer. This will help us to understand how the process of 2D crystalisation via such chelating lipids, which is well known at the air-liquid interface, can be successfully transferred to the solid-liquid interface.