The important role of mice as a model in research of microbe host interactions increased the need for determining the limits of such experiments due to host specificity and adaptation of several microbes. We collected a broad collection of bacteria isolated from mice covering the whole taxonomic range of common gut bacteria. Based on the high functional coverage by this collection of metagenomic gut samples obtained from mice we can use it to simulate several microbial profiles using minimal consortia of bacteria, facilitating the better understanding of the systems.