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Clinical isolate sequencing
Sequencing of several clinical isolates of different species -
Recovery of nearly 8,000 uncultivated bacterial and archaeal genomes substant...
Challenges in cultivating microorganisms have limited the phylogenetic diversity of currently available microbial genomes. This is being addressed by advances in sequencing... -
The mouse intestinal bacterial collection (miBC) represents a unique resource...
The important role of mice as a model in research of microbe host interactions increased the need for determining the limits of such experiments due to host specificity and... -
Drakenstein12internal
This is a large scale project with the sequencing co-funded by collaborators at the University of Cape Town and WT Core (I2818). This is a project aimed at deepening our... -
The Epigenomic Landscape of Prokaryotes
DNA methylation is an important regulator of genome function in the eukaryotes, but it is currently unclear if the same is true in prokaryotes. While regulatory functions have... -
Two weeks in the World 2020
The Two Weeks in the World research project has resulted in a dataset of 3100 clinically relevant bacterial genomes with pertaining metadata, collected from 59 diagnostic units... -
Genomic_and_bacterial_blueprint_of_the_human_gastrointestinal_microbiota
Here we present a comprehensive collection of 737 whole-genome sequenced bacterial isolates from humans to understand the blueprint of human gastrointestinal microbiota. This... -
Clinical evaluation of mNGS in unbiased pathogens diagnosis of UTIs
Advance the implementation of mNGS in pathogen diagnosis in clinics. -
Reliability of species detection in 16S microbiome analysis
The use of NGS-based testing of the bacterial microbiota is often impeded by inconsistent or non-reproducible results, especially when applying different analysis pipelines and... -
FDA-ARGOS is a database with public quality-controlled reference genomes for ...
<b>FDA-ARGOS project update</b> <p>FDA-ARGOS database updates may help researchers rapidly validate diagnostic tests and use qualified genetic sequences to...