Sympathetic Stimulation Can Compensate for Hypocalcaemia-Induced Bradycardia in Human and Rabbit Sinoatrial Node Cells (v1.0)

DOI

This experiment simulates the extended sinoatrial node cell models of Severi et al. (2012) and Fabbri et al. (2017) with several [Ca2+]o and [ISO]. The extension of the AC-cAMP-PKA signalling cascade is based on the work of Behar et al. (2016).

Identifier
DOI https://doi.org/10.35097/qec954fvka86gcjw
Metadata Access https://www.radar-service.eu/oai/OAIHandler?verb=GetRecord&metadataPrefix=datacite&identifier=10.35097/qec954fvka86gcjw
Provenance
Creator Linder, Moritz (ORCID: 0009-0000-1228-159X); Loewe, Axel ORCID logo
Publisher openCARP
Contributor RADAR
Publication Year 2025
Funding Reference European Commission https://ror.org/00k4n6c32 ROR 101172576 https://www.microcard.eu European High-Performance Computing Joint Undertaking EuroHPC (JU) - MICROCARD-2
Rights Open Access; Apache License 2.0; info:eu-repo/semantics/openAccess; http://www.apache.org/licenses/LICENSE-2.0
OpenAccess true
Representation
Language English
Resource Type Software
Format application/x-tar
Discipline Biology; Computer Science; Computer Science, Electrical and System Engineering; Construction Engineering and Architecture; Engineering; Engineering Sciences; Life Sciences; Medicine