Water plays a vital role in biochemical processes in a living organism. Within a cell, intracellular water structure/dynamics are known to be changed by metabolites or extrinsic entities (e.g. drugs), while water properties are prone to affect the function of biomolecules and hence cell viability. Intracellular water may thus be a potential secondary drug target. This is an innovative way for tackling the drug´s pharmacodynamics aiming at an enhanced therapeutic activity.This study aims at exploring this concept for a Pd(II) anticancer agent, following a similar experiment on cisplatin that yielded promising results (OSIRIS/RB1400034 and 1510054). Building on this successful proof-of-concept study, the QENS technique (with isotope labelling) will be used to probe the effect of a Pd(II) anticancer agent on water dynamics in low prognostic triple-negative human breast cancer cells.