Continuous underway measurements of dissolved oxygen and nitrogen were collected during the 2023 Phytoplankton UPwelling response cycle (PUPCYCLE) II expedition from May 27 - June 12, 2023 onboard the R/V Sally Ride. The cruise transited between Newport, OR and San Francisco, CA. Seawater was delivered via the ship's underway seawater supply line (intake depth close to 5m) and passed through a custom-built Pressure In Situ Gas Instrument (PIGI). The PIGI contains an oxygen optode (Aanderaa) paired with a gas tension device. Nitrogen concentrations are derived from the difference between total dissolved gas pressure and oxygen pressure measurements.