Self-assembled Floating Lipid Bilayers: What Forces Are Causing the Bilayer to Surface Distance Control?

DOI

Recently (RB19100102) we have discovered that floating bilayers composed of fluid phase lipids can be produced by deposited vesicles onto charge modified oligo(ethylene glycol)coated gold surfaces. Changing the solution NaCl concentration was found to cause the membrane to surface distance to increase. This effect is likely related to one or a combination of two phenomena. Either secondary hydration forces arising from the binding of hydrated cations to the charged SAM surface or a change in membrane surface charge due to head group ion interactions. We plan to compare the change in bilayer to surface distance using four differing Salt solutions (NaCl, LiCl, NaBr and LiBr) to determine which mechanism is controlling the changes in membrane to surface distance in these new functional membrane mimetics.

Identifier
DOI https://doi.org/10.5286/ISIS.E.RB1920026-1
Metadata Access https://icatisis.esc.rl.ac.uk/oaipmh/request?verb=GetRecord&metadataPrefix=oai_datacite&identifier=oai:icatisis.esc.rl.ac.uk:inv/105605904
Provenance
Creator Professor Mark Sansom; Dr Maxmilian Skoda; Dr Luke Clifton; Professor Gail Preston; Mrs Laura John; Dr Andrew McCluskey; Dr Andreas Haahr Larsen
Publisher ISIS Neutron and Muon Source
Publication Year 2022
Rights CC-BY Attribution 4.0 International; https://creativecommons.org/licenses/by/4.0/
OpenAccess true
Contact isisdata(at)stfc.ac.uk
Representation
Resource Type Dataset
Discipline Biology; Biomaterials; Engineering Sciences; Life Sciences; Materials Science; Materials Science and Engineering
Temporal Coverage Begin 2019-10-02T07:30:00Z
Temporal Coverage End 2019-10-05T07:30:00Z