19 datasets found

MA - Mammography Screening Cohort Samples and data are collected in connection with mammography screenings from 1995-2006. The blood samples consist primarily of EDTA and...

Robust, reliable, and protein-free bacterial membrane mimicking systems compatible with the high through put screening techniques will largely facilitate the discovery of new...

Protein-surfactant interactions at an interface play an important role for broad applications in the chemical, dairy, cosmetic and pharmaceutical industries. Rubisco is the most...

The Gram negative bacterial outer membrane protects the bacterium from toxins such as antibiotics and is partially responsible for the rapid rise in antibiotic resistance in...

Mitochondria are not only the powerhouse of the cell, but are also involved in cellular suicide via apoptosis (programmed cell death). This pathway is a major regulator in cell...

We have developed a Self-assembled floating supported membrane sample system comprised of unsaturated phospholipid bilayers held ~1nm from a PEGylated charged alkane thiol SAM...

The outer membrane of Gram negative bacterial is an effective barrier for many harmful agents. We have been developing and testing advanced models of the Gram negative bacterial...

The aim of the proposed experiment is to carry out a series of SANS measurements on chain-grafted silica nanoparticles prepared in our laboratory. In this experiment we plan to...

We propose to use INS to characterise the structural and vibrational properties of a new class of Fenton-like Fe(IV)O intermediates of potential relevance in the conversion of...

The outer membrane (OM) of gram negative bacteria is mainly constituted of highly polydisperse and amphiphilic lipopolysaccharide (LPS), an endotoxin which is accompanied by...

Recently we have been able to show two advances in the creation of realistic models of the Gram negative bacterial outer surface for use in biophysical and structural studies....

Gram-negative bacteria, which cause a variety of diseases including meningitis, plague, sepsis and food poisoning, are becoming increasingly antibiotic resistant. One reason is...

We have recently improved the stability and coverage of free standing bilayers (FSB) by the use of a supporting thiolipid layer on gold. The system has been investigated on...

The Na+/H+ exchanger isoform 1 (NHE1) is a transmembrane protein with the primary function of regulating the pH in the cytosol by exchanging one proton with one Na+ ion. The...

Lipid membranes provide a sensitive platform for a variety of biological functions, and membrane lipid distributions are carefully regulated. In this project we plan to study...

Tissue Factor (TF) is a membrane protein located on the cell surfaces of extravascular cells. TF activity is fundamental for normal homeostasis- the physiological process which...

Recently (RB19100102) we have discovered that floating bilayers composed of fluid phase lipids can be produced by deposited vesicles onto charge modified oligo(ethylene...

The Gram negative bacterial outer membrane protects the bacterium from external toxins such as antibiotics. This is partially responsible for Gram negative bacteria becoming the...

We have recently improved the stability and coverage of free standing bilayers by the use of a supporting thiolipid layer on gold. The system has been investigated on POLREF and...