The structure of biomimetic helices in aqueous solutions

DOI

Protein secondary structure, in particular alpha-helical structure, is essential for a variety of functions in nature. These structures are integral to such biophysical processes as cell signalling across a biomolecular membrane to binding to DNA for transcription, a process which is essential to all life on earth. In naturally occurring globular proteins, helices are embedded and intercalated with other parts of the this large molecule which yields structural investigations of these structures in solution exceedingly difficult. For this reason biomimeti helices can be used to to mimic real biophysical systems in order to understand specific interactions between protein-helical structures and their surrounding physiological environment.

Identifier
DOI https://doi.org/10.5286/ISIS.E.24090126
Metadata Access https://icatisis.esc.rl.ac.uk/oaipmh/request?verb=GetRecord&metadataPrefix=oai_datacite&identifier=oai:icatisis.esc.rl.ac.uk:inv/24090126
Provenance
Creator Dr Sylvia McLain; Professor Peter Scott; Miss Rebecca Kaner; Dr Sebastian Busch
Publisher ISIS Neutron and Muon Source
Publication Year 2016
Rights CC-BY Attribution 4.0 International; https://creativecommons.org/licenses/by/4.0/
OpenAccess true
Contact isisdata(at)stfc.ac.uk
Representation
Resource Type Dataset
Discipline Photon- and Neutron Geosciences
Temporal Coverage Begin 2012-12-21T08:02:30Z
Temporal Coverage End 2013-02-24T09:07:39Z