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The structure of biomimetic helices in aqueous solutions
Protein secondary structure, in particular alpha-helical structure, is essential for a variety of functions in nature. These structures are integral to such biophysical... -
Dynamics within the Plastic Crystal Phases of Hydrogen Chloride
Hydrogen chloride exhibits a complex phase diagram account made of its simple molecular structure. Three crystalline phases are known to exist at ambient pressure below its... -
Investigations of atomic and intermediate-range structure in model membranes
This proposals aims to investigate the atomic and intermediate range structure in model membrane environments. By beginning with a disperse system of a phosphocholine lipid in... -
Proton Delocalization in Liquid Hydrogen Chloride
Liquid HCl has attracted numerous studies focusing onto the role played by hydrogen bonding on the dynamical properties of this weakly associated liquid. Previous computational... -
Understanding Short Strong Hydrogen Bonds between Anions in Non-Aqueous Solve...
It is undeniable that hydrogen bonding plays a fundamental role in all biological systems. Not only is hydrogen bonding between water and bio-molecules important, but the more... -
Changes of phospholipid aggregate morphology induced by phospholipase hydrolysis
We propose to look at the interaction of the aggregates two phospholipids form with two phospholipase (PL) enzymes, PLA2 and PLC, which hydrolyse different ester groups in the... -
Copy of: Solvation dynamics of the phosopholipid 1,2-dipropanoyl-sn-glycero-3...
It is well known that water is the medium in which the overwhelming majority of biological processes take place. In cell membranes water molecules are thought to be essential to... -
Insight into the atomic and intermediate level structure of spherical and rod...
Here we propose to look at the structure of two phosphocholine lipids, and their larger scale structures in aqueous solution. Depending on the length of the fatty acid chain in... -
Kinetics of amphotericin B interaction with model human and fungal cell membr...
The increasing incidence of pathogenic fungi resistant to treatment with amphotericin B (AmB) has created a demand for novel anti-fungal agents. The successful development of... -
Analysis of magnetic properties via the F-mu-F state in inorganic flourides
Here we propose to investigate the fluroide containing compounds - AgF2, CuF2 and Cs2CuF4. By taking advantage of the F-mu-F coupling wich occurs in these compounds, we will... -
A Total Scattering Study of Dopamine, L-DOPA and Norepinephrine Aqueous Solut...
We request 5 days on Sandals to study the interactions of the neurotransmitters dopamine, L-dihydroxyphenylalanine and norepinephrine in aqueous solution. The interactions of... -
Solvation dynamics of the phosopholipid 1,2-dipropanoyl-sn-glycero-3-phosphoc...
It is well known that water is the medium in which the overwhelming majority of biological processes take place. In cell membranes water molecules are thought to be essential to... -
The structure of pharmaceuticals in aqueous solution: towards better drug sol...
The pharmaceutical industry has been described as being 'in a period of crisis' as the number of drug approvals relative to most major pharmaceutical companies Research and... -
Investigation of the structure of self-assembling peptide fibrils using neutr...
A consortium of several UK universities and industries has been set up, based at the National Physical Laboratory, Teddington, to investigate ¿Length-scale bridging in... -
The structure of ceramides in a model membrane environment
This proposal aims to investigate the structure of ceramide, an important component of cellular membranes in a mimic membrane environment. After assessment of this molecule in... -
V plate 3mm SC Pos 0 25C Jaws 30x30mm2 Beam Scraper 30mm diameter
This dataset has no description
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Investigation of phosphatidylcholine and its interaction with 1,2 propandiol ...
The aim of the present study is to use neutron diffraction enhanced with isotopic substitution and subsequent computer simulations to determine the head group solvation of a...
