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Structure of responsive PNIPAM-PAAc microgels
We propose to investigate a temperature and pH responsive microgel composed of Interpenetrating Polymer Networks (IPN) of poly(N-isopropylacrylamide) (PNIPAM) and poly(acrylic)... -
SANS Studies of Novel Internally Stabilised Liposomes
Internally supported liposomes (ISLs) are composed of polymeric spheres enclosed by liposomes. Although very little research has been done on ISLs, understanding their... -
Concentrated emulsions as proxy CO2 thickeners
The proposal aims to explore the oil-in-water (brine) high internal phase emulsion systems (HIPEs) formed by nonylphenol ethoxylate surfactants using contrast variation SANS... -
Solventless protein liquids: a novel form of biological matter
Solventless protein liquids (SPLS) represent a novel form of biological matter. Recently we reported on the preparation and properties of a solvent-free liquid protein based on... -
Compartmentalised Supramolecular Structures through CB[8]-mediated Hierarchic...
We have recently developed a method to prepare a wide variety of amphiphilic diblock copolymers through a supramolecular linkage that is stable in water. This has been achieved... -
Changes of phospholipid aggregate morphology induced by phospholipase hydrolysis
We propose to look at the interaction of the aggregates two phospholipids form with two phospholipase (PL) enzymes, PLA2 and PLC, which hydrolyse different ester groups in the... -
Kinetics of the formation of eumelanin and its intermediates
The proposed research project is targeted to the investigation of the characteristics of eumelanin, a heterogeneous material insoluble in water and in any organic solvent, as... -
SANS characterization of carbonate reservoir formation and evolution
Geologists are increasingly realizing the unique perspective that neutron scattering offers for unlocking the complex geologic histories of rocks. In this study, we propose to... -
Structure of siRNA containing delivery vehicles: effect of serum
Complexes prepared from cationic, dichain lipid (L) vesicles and negatively charged siRNA (R), with and without positively chargely targeting peptides (P) known as LR or LPR... -
Gels in CO2
The proposal aims to explore different self-assembly structures in CO2 with the focus of developing viscosity modifiers for supercritical CO2 (sc-CO2). This is part of a... -
Self-assembly of nonionic surfactant in alcohol/water from room temperature t...
Surfactant self-assembly has been extensively studied in aqueous solution at room temperature or above, but it was less documented at temperatures below 0 °C. Our preliminary... -
Responsive polymer brushes grafted from gold nanoparticles: interaction with ...
We will use SANS to characterize dispersions of gold nanoparticles functionalized with poly(dimethyl aminoethyl methacrylate) brushes grafted from 25 nm gold nanoparticle... -
SANS study of synthesis of interpenetrating polymer networks in supercritical...
We use SANS to study synthesis of interpenetrating polymer network in supercritical CO2 in situ at sans2D. The initial system contains an inorganic polymer network, hydrophilic... -
Morphology and Phase Diagram of Thermoresponsive Polymer-Protein Conjugates
Using an enzyme mediated conjugation method we have prepared well-designed protein-polymer conjugates using a model protein, green fluorescent protein (GFP) with... -
Investigation on the structural properties of doxorubicin-loaded PEGylated li...
Doxil® is a marketed liposomal formulation containing the anticancer drug doxorubicin. Recently, SAXS measurements have evidenced a crystalline fibrillar structure for the...