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Effect of pH on the complexation behaviour between Pluronic micelles, drugs a...
Pluronic micelles are attractive candidates as drug carriers. Despite the abundance of data on their association with various drugs, there is, in contrast, very little... -
Self-assembly of protein polymer conjugates: Effect of copolymer structure
Conjugation of therapeutic proteins to polymers is well established but most methods result in multi-site and multiple conjugation or crosslinking resulting in lack of... -
Unravelling the solution structures and stability of industrially-important a...
The glycosylation of glycoproteins is a major determinant of their stability, and glycans also affect their aggregatibility (precipitation). An understanding of this is... -
Perylene Bisimide Photocatalysts
Solar energy is the most abundant, sustainable, and environmentally friendly source of energy available on the earth. One promising approach to reducing the reliance on fossil... -
Probing chiral interactions in aqueous amino acid deriving polymers
Sodium deoxycholate (NaDC) is a low molecular weight gelator, widely known as one of the components of bile salts. Above a specific concentration, NaDC is able to form pH... -
Self-assembly of GFP-HMPA protein polymer conjugates: Effect of polymer hydro...
Conjugation of therapeutic proteins to polymers is well established but most methods result in multi-site and multiple conjugation, crosslinking resulting in lack of orientation... -
Pickering emulsions stabilized with oxidised cellulose nanofibrils and starch
Our group has been working functionalised cellulose nanofibrils which form gels in aqueous formulations. Previously we have used these fibrils to stabilise oil-in-water... -
Novel materials for heat storage application: a small-angle neutron scatterin...
Large quantities of thermal energy can be stored reversibly in composite materials containing SrCl2 and Expanded Natural Graphite (ENG) upon exo-/endothermal ab-/desorption of... -
interaction of a pharmaceutical water-soluble polymer with bio-relevant surfa...
We have been developing hydroxypropylmethyl cellulose (HPMC) microspheres for delivering poorly water-soluble drugs. The in vitro dissolution data showed that the presence of... -
Kinetic Study of the Mechanistic Complexation Process Between DNA and Cationi...
We propose to use the new SANS2d to study the dynamic structural evolution in the couse of the formation of DNA-cationic polymer complexes. The dynamic process and the mixing... -
Micelle structures in unequal mixtures of amino-acid surfactants
In a previous proposal we started to study the micellar structures formed from biodegradable surfactants synthesised using amino acids as the headgroups. The aim of this work is... -
Anion effects on self-assembly in deep eutectic solvents.
Deep Eutectic Solvents (DES) are mixtures of an organic salt with a hydrogen bond donor that form strong interactions which hinder crystallisation. DES share many features with... -
Structure of chain-grafted silica nanoparticles
The aim of the proposed experiment is to carry out a series of SANS measurements on chain-grafted silica nanoparticles prepared in our laboratory. In this experiment we plan to... -
FRET-based Conjugated Polymer Macromolecular Switch for Bio-Anion Recognition
We intend to study the aggregation behaviour of the all-conjugated block catiocopolyelectrolyte PF2/6-P3MAHT in the presence of the biomacroanion guanosine triphosphate (GTP) in... -
Effect of surfactant head group on micelle structure of drug containing micelles
The aim of the current project is to probe (at the nanometer length scale) the relationship between the solution structures of a surfactant molecule, the aggregate(s) it forms... -
SANS investigation of proteins trapped in hydrogels formed by binary mixtures...
Aqueous solutions of guanosine 5-monophosphate (GMP) can turn into isotropic gels by the addition of guanine (Gua). The Gua:GMP hydrogel property of including a significant... -
Interaction of keratin with surfactants studied by SANS
This proposal constitutes part of our ongoing study towards understanding how keratin, an important protein component of hair and skin, interacts with ionic surfactants using... -
Interaction of keratin with surfactants studied by SANS
This proposal constitutes part of our ongoing study towards understanding how keratin, an important protein component of hair and skin, interacts with ionic surfactants using... -
Structure in Polymer Conetworks
This proposal is part of a new research programme at Reading which is focused on a new types of macromolecular structures namely conetworks and pseudo-conetworks. These are... -
Microemulsion Controlled Polymorph Crystallisation
Control of crystallisation is essential for many applications ranging from pharaceuticals to packaging and food preservation, yet remains extremely challenging. Recently we have...