157 datasets found

We propose to investigate a temperature and pH responsive microgel composed of Interpenetrating Polymer Networks (IPN) of poly(N-isopropylacrylamide) (PNIPAM) and poly(acrylic)...

Staphylococcus aureus is a normal skin commensal and an opportunistic pathogen that presents serious threat to healthcare. It is the causative agent of septicaemia and...

This proposal is part of a project based on understanding the formation of gels in suspensions of partially oxidised cellulose nanofibrils and small amounts of additives, such...

Cyclic peptides with alternating side chain stereochemistry are capable of self-assembling into long nanotubes. The conjugation of polymers to these peptides renders the...

In cells, the genome needs to be tightly packaged in the nucleus as "chromatin" while still allowing access to the cellular machinery responsible for gene expression. The first...

Polyurethane foams (PUFs) are commonly prepared by mixing Pluronic type copolymers and isocyanate reactive monomers in the presence of additives e.g. catalysts, blowing agent...

Internally supported liposomes (ISLs) are composed of polymeric spheres enclosed by liposomes. Although very little research has been done on ISLs, understanding their...

Liquid pharmaceutical formulations are commonly comprised of proteins and surfactants, which interact in solution in order to provide an increase in system stability. Although...

Soft self-assembled structures have been extensively used as drug nanocarriers. Their building blocks, naturally occurring and synthetic amphiphiles (lipids or block...

The aim of this project is to develop an understanding of the relationships between the processing, nanoscale structure and device performance of bulk heterojunction,...

The glycosylation of glycoproteins is a major determinant of their stability, and glycans also affect their aggregatibility (precipitation). An understanding of this is...

Gradient and block copoly(2-oxazoline)s have been prepared comprising a partially deuterated hydrophilic poly(2-methyl-2-oxazoline) part and a hydrogenated...

In the proposed experiments we extend previous work on characterization of aggregates formed by cationic conjugated polymers and oligomers in water. Particular emphasis will be...

Ultrasound is a very attractive and patient-friendly imaging technique, as it is easy to use, fast and non-invasive. Nevertheless, its use is severely limited by the low...

Magnetic skyrmions are vortex-like, magnetic-spin objects that were lately discovered in bulk chiral magnetic materials. Recently, we discovered super stable magnetic...

The very heterogeneous, but non-random, arrangement of lipids and proteins in cell membranes are of major scientific interest and led Simons and Ikonen to propose that ¿rafts,¿...

Sodium dodecyl sulfate (SDS) is an anionic surfactant, extensively employed in cosmetics and personal care, as well as in pharmaceuticals and food products. Surfactants are...

The aim of the study is to use SANS in combination with contrast variation to determine the effect of solubilising the lipophilic drug, testosterone propionate, in micelles...

Major technological and scientific challenges arise from the pressure to provide widely available and sustainable technologies for the societal requirements for health and a...

Cytochromes P450 play a key role in drug metabolism in man. Electrons are supplied to the cytochromes by NADPH through the flavoprotein NADPH-cytochrome P450 reductase (CPR)....