Experimental data of the manuscript "Improved biosensing of Legionella by integrating filtration and immunomagnetic separation of the bacteria retained in filters"

DOI

Experimental data of the manuscript "Improved biosensing of Legionella by integrating filtration and immunomagnetic separation of the bacteria retained in filters", published in Microchimica Acta, https://doi.org/10.1007/s00604-023-06122-1. This study presents a novel approach that combines filtration and the direct immunomagnetic separation of the retained bacteria Legionella in filters, for further electrochemical immunosensing. This strategy allows for the separation and preconcentration of the water-borne pathogen from high-volume samples, up to 1000 mL. The limit of detection of the electrochemical immunosensor resulted in 100 CFU mL−1 improved to up to 0.1 CFU mL−1 when the preconcentration strategy was applied in 1 L of sample (10^3-fold improvement). Remarkably, the immunosensor achieves the limit of detection in less than 2.5 h and simplifying the analytical procedure. This represents the lowest concentration reported to date for electrochemical immunosensing of Legionella cells without the need for pre-enrichment or DNA amplification. Furthermore, the study successfully demonstrates the extraction of bacteria retained on different filtering materials using immunomagnetic separation, highlighting the high efficiency of the magnetic particles to pull out the bacteria directly from solid materials. This promising feature expands the applicability of the method beyond water systems for detecting bacteria retained in air filters of air conditioning units by directly performing the immunomagnetic separation in the filters.

Identifier
DOI https://doi.org/10.34810/data1015
Related Identifier IsCitedBy https://doi.org/10.1007/s00604-023-06122-1
Metadata Access https://dataverse.csuc.cat/oai?verb=GetRecord&metadataPrefix=oai_datacite&identifier=doi:10.34810/data1015
Provenance
Creator Mesas Gómez, Melania ORCID logo; Molina‑Moya, Barbara ORCID logo; Souza, Bárbara de Araujo; Boldrin Zanoni, Maria Valnice ORCID logo; Julián Gómez, Esther ORCID logo; Domínguez, José; Pividori Gurgo, Maria Isabel ORCID logo
Publisher CORA.Repositori de Dades de Recerca
Contributor Pividori Gurgo, Maria Isabel; Universitat Autònoma Barcelona
Publication Year 2024
Funding Reference Agencia Estatal de Investigación PID2019-106625RB-I00 ; Agència de Gestió d'Ajuts Universitaris i de Recerca 2017/SGR-220 ; Agència de Gestió d'Ajuts Universitaris i de Recerca 2021/SGR-00124 ; Agència de Gestió d'Ajuts Universitaris i de Recerca 2021/SGR-00092 ; Agència de Gestió d'Ajuts Universitaris i de Recerca 2021/SGR-1267 ; Agencia Estatal de Investigación FPI/BES-2017-080748
Rights CC BY 4.0; info:eu-repo/semantics/openAccess; http://creativecommons.org/licenses/by/4.0
OpenAccess true
Contact Pividori Gurgo, Maria Isabel (Universitat Autonoma de Barcelona. Departament de Química)
Representation
Resource Type Experimental data; Dataset
Format application/vnd.openxmlformats-officedocument.spreadsheetml.sheet; text/plain
Size 2248666; 4953
Version 1.1
Discipline Chemistry; Natural Sciences