The acyl-L-carnitines are a group of novel surfactants. Following our recent home laboratory work to synthesize, purify and characterize them, the aim of this proposal is to examine how they adsorb on surface of water and then how they bind to model lipid monolayers mimicking charged bacterial membranes by neutron reflection. The proposed neutron work offer unique data about the adsorption of this group new surfactants under different pH and ionic strength and their binding to lipid monolayers to mimic bacterial membranes. We have recently prepared the acyl chain deuterated acyl-L-carnitines. This will be the first neutron reflection study of this group of novel synthetic biosurfactants.