We present new results of our UBV photometry for HD 179821=V1427 Aql, an F supergiant with an infrared excess, from 2000 to 2008. The semiregular low-amplitude ({Delta}=0.05-0.20mag) photometric variability of the star with a cycle period from 130 to 200 days is caused by pulsations, along with the instability of a variable stellar wind. V1427 Aql also exhibits a long-term trend in the brightness and colors that is probably attributable to a change in the stellar temperature as a result of mass loss episodes, which cause variations in the continuum formation level. We present the results of our JHKLM photometry for V1427 Aql in 1992-2008.