Cholesteryl Ester Transfer Protein (CETP) as a Drug Target for Cardiovascular Disease

DOI

Contains data and computer scripts to generate the figures underlying the manuscript: Cholesteryl Ester Transfer Protein (CETP) as a Drug Target for Cardiovascular Disease.The README.md:# Scripts and deposited data This directory contains R and python scripts along with the data necessary to generate the results described in the manuscript: 'cholesteryl ester transferprotein (CETP) as a drug target for cardiovascular disease'. ## Directory content .├── README.md├── scripts├── figures├── MR_data├── TRIAL_data└── PICKLED_dataThe scripts directory contains the computer codes necessary to generate the figures which get saved to the figures directory.The scripts source data from the MR_data and TRIAL_data directories. The PICKLED_data directory contains the python pickled files from which we extracted the .csv files in MR_data -- these files can be ignored. ## Computer scriptsThe directory root contains various R (.R) and python (.py) scripts that will process the data files. It also contains a cetp_conda_env.yml file to conda install the necessary R and python modules:cd scriptsconda env create -f cetp_conda_env.ymlThis creates the cetp conda environment. To generate the figures, please run the following bash script:# run from the scripts directory./run_scripts.sh### Input and output scripts/MR_heatmap.py: Takes the MR_data .tsv files and returns Figures 2 and 5. scripts/MR_metabolites.R: Takes the MR_data .tsv/csv files and returns Figure 4. scripts/MR_forestplots.R: Takes the MR_data .tsv files and returns Figure 3. scripts/RCT_forestplots.R: Takes the TRIAL_data .xlsx files and returns Figure 1.## ContactPlease contact Floriaan Schmidt for any queries: amand.schmidt@ucl.ac.uk .

Identifier
DOI https://doi.org/10.5522/04/13686247.v3
Related Identifier https://ndownloader.figshare.com/files/28998069
Metadata Access https://api.figshare.com/v2/oai?verb=GetRecord&metadataPrefix=oai_datacite&identifier=oai:figshare.com:article/13686247
Provenance
Creator Schmidt, Floriaan ORCID logo
Publisher University College London UCL
Contributor Figshare
Publication Year 2021
Rights https://creativecommons.org/licenses/by-sa/4.0/
OpenAccess true
Contact researchdatarepository(at)ucl.ac.uk
Representation
Language English
Resource Type Dataset
Discipline Life Sciences; Medicine