Self-assembling behaviour of N-acyl amino acid-based surfactants

DOI

N-acyl amino acids are surfactants with attractive applications in different technological fields. They are referred to as mild surfactants because they are commonly considered less irritant and safer than sulfates anionic surfactants. N-acyl amino acid surfactants could infact represent an alternative and safer option to SDS. However, the full potential of such surfactants remains unexplored, mainly because of the lack of information regarding a full characterization of their physicochemical and toxicological properties, including their interaction with biological membranes.With the aim to use these compounds as drug delivery agents,we propose here to study their self-assembly behavior in solution. This is uniquely possible by SANS and will help understanding their shape, loading and temperature stability.This study will help us proceeding further in their application in real systems.

Identifier
DOI https://doi.org/10.5286/ISIS.E.82701683
Metadata Access https://icatisis.esc.rl.ac.uk/oaipmh/request?verb=GetRecord&metadataPrefix=oai_datacite&identifier=oai:icatisis.esc.rl.ac.uk:inv/82701683
Provenance
Creator Professor Luca Casettari; Dr Diego Romano Perinelli; Dr Mario Campana; Dr James Doutch
Publisher ISIS Neutron and Muon Source
Publication Year 2019
Rights CC-BY Attribution 4.0 International; https://creativecommons.org/licenses/by/4.0/
OpenAccess true
Contact isisdata(at)stfc.ac.uk
Representation
Resource Type Dataset
Discipline Biology; Biomaterials; Chemistry; Engineering Sciences; Life Sciences; Materials Science; Materials Science and Engineering; Medicine; Natural Sciences; Physics
Temporal Coverage Begin 2016-10-13T23:00:00Z
Temporal Coverage End 2016-10-17T23:00:00Z