This data set contains microscopic photographs of in vitro cultures of Human Microvascular Endothelial Cells (HMEC-1) spheroids used to test role of Apelin and its receptor in angiogenic sprouting. It is used to test a hypothesis developed using computational modeling of angiogenesis. Images in TIFF format, as used for the image analysis. The archive also includes the output files of the NeuronJ plugin to ImageJ (file extension ".NDF") as well as XML-files containing microscopy settings.The dataset set is part of the publication "Computational Screening of Tip and Stalk Cell Behavior Proposes a Role for Apelin Signaling in Sprout Progression”.

Date Submitted: 2015-08-05

Files not yet migrated to Data Station. Files for this dataset can be found at https://easy.dans.knaw.nl/ui/datasets/id/easy-dataset:61903.

Please note: the files cannot be downloaded from EASY all at once due to the large number of files and file size. Please contact DANS for assistance via info@dans.knaw.nl.2016-10-13: The dataset title and creators were previously listed as: "Dallinga, M.G. (Academic Medical Center - AMC); Klaassen, Dr. I. (Academic Medical Center - AMC); Schlingemann, Prof.dr. R.O. (Academic Medical Center - AMC) (2015): Dataset S2 of "Computational Screening of Tip and Stalk Cell Behavior Predicts a Role for Apelin Signaling in Sprout Progression"."2016-11-14 The related publication is now available in the dataset, the pre-print, 1409.5895v2.pdf, is no longer accessible.