In low-pressure methanol synthesis from fossil synthesis gas, Cu/ZnO/Al2O3-catalysts are successfully used in industrial synthesis at 250°C and 50-100 bar, but the exact mechanism of this reaction is still not fully understood. We propose bi-metallic stepped facets like CuZn(211) as the CO2-converting centers, suggesting a crucial role of Zn as component of the active surface ensemble. With the proposed experiment we would like to study the role of the so-called Cu-Zn synergy for methanol synthesis with INS. Preliminary ex-situ feasibility studies of a post-reaction Cu/ZnO/Al2O3-catalyst have revealed a surface coverage of hydroxyl and methoxy on the catalyst. A successful experiment will contribute to the understanding of the active site in methanol synthesis, which is one prerequisite for the rational design of more efficient as well as sustainable methanol catalyst of the future.