Cellulose-based polyelectrolytes for microencapsulation: conformational transitions triggered by multivalent salts

DOI

Addition of multivalent salts to water soluble polyelectrolytes, such as sodium carboxymethyl cellulose (NaCMC), induces conformational change to the polyelectrolyte structure, resulting in aggregation and precipitation, or gel formation, with increasing salt concentration. We have demonstrated that this transition can be exploited with NaCMC for encapsulation, specifically with microfluidic techniques. Whilst the phenomena has been previously reported, the complex effects of salt addition on polyelectrolyte conformation (charge screening, ion bridging and charge inversion) have not been fundamentally answered. We aim to address the equilibrium state of polyelectrolyte-salt mixtures, and mechanistic understanding of the conformational transition, to enable us to precisely design a (non-equilibrium) framework for directional solidification of these materials for encapsulation.

Identifier
DOI https://doi.org/10.5286/ISIS.E.92921745
Metadata Access https://icatisis.esc.rl.ac.uk/oaipmh/request?verb=GetRecord&metadataPrefix=oai_datacite&identifier=oai:icatisis.esc.rl.ac.uk:inv/92921745
Provenance
Creator Dr Sarah Rogers; Mr Carlos Gonzalez Lopez; Dr Carlos Lopez; Dr William Sharratt; Professor Joao Cabral; Miss Roisin O'Connell
Publisher ISIS Neutron and Muon Source
Publication Year 2021
Rights CC-BY Attribution 4.0 International; https://creativecommons.org/licenses/by/4.0/
OpenAccess true
Contact isisdata(at)stfc.ac.uk
Representation
Resource Type Dataset
Discipline Chemistry; Natural Sciences
Temporal Coverage Begin 2018-05-11T08:00:00Z
Temporal Coverage End 2018-05-13T10:52:05Z