Peptide-functionalized nanoparticle (NP) aggregates have significant potential as biosensors (for specific enzymes) due to their high sensitivity, modular design and simple colourimetric change in response to stimuli. In order to extend the system to different enzymes a better understanding of the response kinetics is required. We propose to use SANS to probe NP-peptide aggregation and triggered dispersion in real-time. Quantitative information describing the change in size, inter-particle spacing and ordering of NP aggregates will be derived from these data. Information on the rate and degree of enzyme cleavage would be used to quantitatively understand and optimise the factors affecting the efficiency of dispersion. The characteristic colour of NP suspensions is dependent on their separation, size and size distribution, necessitating detailed, accurate information on these properties.