Three - dimensional reconstruction of time-resolved disintegration process in pharmaceutical tablets

DOI

This dataset contains time series of reconstructed image stacks, one set per tablet composition. The reconstructed image stacks were binned from their original resolution to suit the memory constraints of our deep learning image segmentation algorithm. Each time series of reconstructed image stack is supplemented by its equivalent time series of segmented image data. The dataset additionally contains the hand-segmented data that was used to train the CNN.

This dataset is structured as follows: For each tablet formulation (N1 to N64), a folder is available containing the full time series of reconstructed image stacks (1 HDF5 file per time point). A second folder is available for each formulation containing the same series of image stacks in segmented form (1 HDF5 file per time point). The trained U-Nets used for the segmentation of the data are available in a separate folder, along with the hand-segmented data used to train these networks. Lastly there is a ‘readme’ folder containing documents detailing acquisition parameters as well as details on the composition of the different tablets.

Identifier
DOI https://doi.org/10.16907/3ebf3cd2-498c-4278-a652-9d24ad413c49
Metadata Access https://doi.psi.ch/oaipmh/oai?verb=GetRecord&metadataPrefix=oai_dc&identifier=10.16907/3ebf3cd2-498c-4278-a652-9d24ad413c49
Provenance
Creator Samuel Waldner, Maxim Puchkov, Christian M. Schlepuetz
Publisher PSI
Publication Year 2022
Rights Available to the public.
OpenAccess true
Contact PSI
Representation
Resource Type Dataset
Discipline ['Life Sciences', 'Biology', 'Basic Biological and Medical Research']