Despite PI changes, the BAG will continue to work on diverse areas of structural biology, ranging from fundamental of enzyme mechanisms, structure-based engineering of enzymes for industrial applications, particularly involving degradation and transformation of plant biomass, and viral, microbial and mammalian proteins involved in different aspects of health and disease. Among the specific targets are glycosyltransferases, fluorinases, sterol and sugar transporters, NS5B, Keap1, lytic polysaccharide monooxygenases, glucuronylesterases, phage repressor peptidase, alginate degrading polysaccharide lyases, mucin degrading glycosylhydrolases, type V autotransporters.