Research expedition M113-2 SpaDE took place from January 24th, 2015 (Ponta Delgada, Portugal) to February 9th, 2015 (Kingston, Jamaica). CTD data for 22 stations were recorded with a Seabird Electronics (SBE) 9 plus CTD (SN 979) mounted in a SBE water sampler rosette. The data files contain the data for temperature, salinity, density, chlorophyll a concentration and dissolved oxygen concentration; as raw data and processed and flagged according to the recommendations for real-time data processing of EuroGOOS and GTSPP, as well as the outlier detection method CoTeDe (https://github.com/castelao/CoTeDe). Biogeographic regions are determined according to Spalding et al. (2012). TEOS-10 unit conversions have been performed with the GSW Oceanographic Toolbox (McDougall and Barker, 2011).