Scientific projects of the IBS synchrotron group

DOI

We study the structures of a broad diversity of macromolecules from fluorescent to metabolic proteins. One of our primary focus is on solving the 3D structures of enzymes within the MEP pathway, as they represent promising drug targets. Additionally, we are engaged in characterizing new fluorescent proteins derived for instance from bacteriophytochrome. Our research activities also include the development of instrumentation and methodologies, spanning from crystallization to room temperature data collection. We strive to enhance crystal quality for both X-ray and neutron diffraction. Furthermore, we conduct high-throughput screening (HTS) of chemical libraries to identify active ligands targeting proteins with pharmaceutical relevance.

Identifier
DOI https://doi.org/10.15151/ESRF-ES-2066300024
Metadata Access https://icatplus.esrf.fr/oaipmh/request?verb=GetRecord&metadataPrefix=oai_datacite&identifier=oai:icatplus.esrf.fr:inv/2066300024
Provenance
Creator Samuel HJORTH JENSEN; Sylvain ENGILBERGE ORCID logo; LUCAS PETIT
Publisher ESRF (European Synchrotron Radiation Facility)
Publication Year 2028
Rights CC-BY-4.0; https://creativecommons.org/licenses/by/4.0
OpenAccess true
Representation
Resource Type Data from large facility measurement; Collection
Discipline Particles, Nuclei and Fields