Carbohydrates are compounds most vital for all living organisms. Thanks to their multiple hydroxyl groups they can create numerous short-range interactions. Therefore they are the perfect study case to examine the nature of intermolecular contacts such as OH...O and CH...O hydrogen bonds. As it was recently shown for sucrose and glucose, two of the most common sugars, high pressure can significantly influence their crystal structure leading to phase transitions. High-pressure polymorphs of sugars were proven to have different H-bonding patterns in comparison to their ambient-condition forms. Yet, data collected till now were based only on X-ray diffraction experiments. Neutron diffraction is needed to precisely determine positions of hydrogen atoms in the structure and gain insight into the nature of high-pressure transformations of short-range interactions they are involved in.