Deep-sea pollen records from the Western European margin show that during the Last Glacial period, regional vegetation oscillated between steppe and open forest in response to the millennial scale climate variability, Dansgaard-Oeschger, (D-O) cycles and Heinrich events (HE), and that the magnitude of the forest expansions during D-O warming events was modulated by orbital parameters. We present new well-chronologically constrained high-resolution marine pollen records from the Gulf of Lion and Bay of Biscay documenting the NW Mediterranean and SW France vegetation response during Marine Isotope Stages (MIS) 4 and 3 (67-33 ka). The vegetation of these regions is reconstructed by pollen analysis.This dataset presents the composition of vegetation in SW France during the Last Glacial Period (65-35 ka), in particular the pollen taxa recorded in core MD04-2845 (45°21'N, 5°13'W, 4175 m).