The data set has been obtained on gravity core M125-67-4 from off the Jequitinhonha River, East Brazil. The obtained proxies described the hydrological conditions in the river's hinterland over the past ~ 5000 years as measure of fluctuations in the South American Summer Monsoon intensity. XRF-derived K/Al ratios and mineral phases determined by XRD reflect weathering state in the hinterland; high K/Al ratio and low kaolinite contents indicate dry conditions (and vice versa for low K/Al and high kaolinite conditions). Hydrogen isotopes are interpreted to primarily reflect precipitation amount, with low values indicating more precipitation.