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Enzyme-catalysed templating of biosilica
Summary. Silicatein in marine sponges catalyses the condensation of silica but the mechanism of layer-by-layer growth of the silica spicule is unknown since sufficient... -
An immunoassay for the detection of IGFBPs: surface characterisation
Summary: The FIII9'10 domain pair is an antibody light chain mimic which we serendipitously found binds IGFBP-5, a therapeutic target in late stage prostate cancer. An... -
Characterisation of bioadhesive protein-PEG conjugates grafted to titanium su...
Summary: Titanium implants are surgically important and require a hydrophilic polymer coating to prevent biofouling in situ. Bioadhesive proteins can be covalently tethered to... -
Antibody-polysorbate surface interactions
Of concern to the bioprocessing industry is the manner in which polysorbates included in solution formulations of antibodies affect the kinetics and equilibrium state of...