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Non-lamellar lipid-based liquid crystalline structures at interfaces - effect...
To understand better the properties of non-lamellar liquid crystalline nanoparticles, LCNP, as delivery vehicles or surface modifying systems, it is crucial to understand how... -
Surfactant adsorption onto model surfaces
In the context of home and personal care products, studying surfactant and mixed surfactant adsorption ion model solid surfaces, which mimic real surfaces such as fabrics, hair... -
The effect of dendrimer surface functionalization on the interaction with mod...
Dendrimers are a unique class of nano-structured vehicles for drug and gene delivery into intracellular targets. Their surface chemistry influences their transport across... -
The use of lipid sponge-like nanoparticles as carriers for macromolecules and...
Biological membranes do not only occur as planar bilayer structures, but bilayers have also been shown to, depending onthe lipid composition, curve into intriguing 3D... -
Role of apolipoprotein E variant on HDL interactions at model cell membranes
Atherosclerosis is the leading cause of death in western society, its consequences such as strokes and heart attacks arise from the build-up of plaques of fat which accumulate... -
Structure of oxidised phospholipid bilayers
Biological membranes protect cells and are essential for their survival and damaged membranes may cause serious harm to the cell. A primary cause of damage to membranes is... -
Interaction of lamellar and non-lamellar lipid mesophases with inorganic nano...
The behavior of inorganic nanoparticles (NPs) with biological interfaces is a key research topic, to boost Nanomedicine development. In this respect, 2D lipid assemblies are... -
Investigation of PVC plasticizers on phospholipid monolayers
Plastic bags are used as containers for storage of donated blood. These bags are typically made out of PVC plasticized with dialkylphthalates (e.g. DEHP), which migrates into... -
Self-assembling antimicrobial peptides: interactions with model lipid membranes
We propose to investigate antimicrobial peptides that self-assemble into well-defined nanostructures. Previous SAXS results have shown that the peptides form rather robust... -
Interaction between RNA and lipid monolayers
The objective of the suggested study is to reveal the structure formed when short ssRNA molecules (similar to miRNA) interact with lipid monolayers at the air-water interface.... -
Interfacial adsorption of single alkyl chain PC surfactants (CnPmC)
We propose to investigate the interfacial adsorption of a series of water-soluble single chain PC surfactants using neutron reflection, focusing on assessing the effects of... -
Neutron reflectometry of an atopic dermatitis stratum corneum skin model
Atopic dermatitis (AD) is a chronic inflammatory skin condition affecting up to 20% of children and 3% of adults, resulting in significant reduction in quality of life and costs... -
Lipid exchange between high density lipoprotein (HDL) and model phosphatidylc...
Lipoproteins are the main carriers of lipids in the body. HDL is believed to favor cholesterol removal and decrease the risk to develop atherosclerosis and related... -
Interactions of polyfluorinated substances with a phospholipid bilayer
Poly- and perfluoroalkyl substances (PFASs) have been used in various industrial applications and consumer products, but have received increasing global concern due to their... -
Structure of Zwitterionic Surfactants of Varying Headgroup: Interaction with ...
Zwitterionics (here, alkyldimethylammonium carboxybetaines) are widely used in applications which require "mildness", e g cosmetics and isolation of membrane proteins, although...
