-
DPPC bilayer oxidation by aqueous singlet oxygen
The oxidation of membrane lipids by reactive Oxygen Species, ROS, is implicated in cell apoptosis, cancer and ageing. We have performed preliminary experiments studying the... -
The interaction of oxidatively damaged lung proteins with anionic lipids
Lung surfactant protein B, SP-B, interacts with lipids at the air-water interface of the lung where its presence is vital for correct respiratory function. SP-B and its... -
DPPC bilayer oxidation by aqueous singlet oxygen
Oxidation of membrane lipids by Reactive Oxygen Species, ROS, in cells may impact ageing, cell apoptosis and cancer. We propose to use our skills obtained studying the oxidation... -
Changes to the structure of natural lung surfactant, and extracted proteins, ...
The presence of a monolayer of surfactant material at the air-water interface of the lung is crucial for respiratory function. It is well known that exposure to the ubiquitous...
