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Unusual structural change in geminis above the critical micelle concentration
gemini surfactants are essentially two surfactants joined by a linking chain. We have extensively explored cationic geminis at the air/water interface and they exhibit a range... -
Non-ionic surfactant induced desorption of a strongly bound cationic layer fr...
In this proposal we request beamtime to study the unexpected behaviour of a strongly bound bilayer of the cationic surfactant didodecyldimethylammonium bromide on the anionic... -
Organization of mitochondrial membranes upon oxidative stress: Impact on apop...
Mitochondria are not only the powerhouse of the cell, but are also involved in cellular suicide via apoptosis (programmed cell death). The mitochondrial apoptotic pathway is a... -
Contrast variation studies of novel binary polypeptide gels
Low molecular weight gelators (LMWG) form hydrogels via self-assembly in water under specific conditions to form long, fibrillar structures. Non-covalent forces interactions... -
Constructing analogues of gemini and oligomeric surfactants through noncovale...
Gemini-like and oligomeric-like surfactants can be constructed by single-chain or gemini surfacants with connecting molecules through noncovalent binding without complicated... -
Kinetic Study of the Mechanistic Complexation Process Between DNA and Cationi...
We propose to use the new SANS2d to study the dynamic structural evolution in the couse of the formation of DNA-cationic polymer complexes. The dynamic process and the mixing... -
Multilayering of Isostearic Methyl Ester Sulphonate at the Air-Aqueous Interf...
Surfactants usually form a single layer of molecules at the surface of water. We have shown that under certain conditions more than one layer may form. in which case the system... -
Interaction of polypeptides with surfactants: aqueous solution aggregation
This proposal constitutes part of our ongoing study towards understanding how collagen based polypeptides interact with ionic surfactants using SANS. Both SDS and C12TAB will be... -
Phase diagram of LAS molecule: SANS investigation into surfactant and lipid m...
This proposal would like SANS time to better understand the LAS phase diagram. This has been prompted by recent experiments which show the system is not fully understood under... -
Structural characterisation of an electron-transfer protein, cytochrome c, on...
This proposal concerns the adsorption behaviour of an electron-transfer protein, cytochrome c, on modified electrode surfaces. Cytochrome c plays an important role in... -
Capture and isolation of radicals by green tea antioxidants
Molecular modelling suggests that the antioxidant molecule EGCG "folds up" around the radical it captures, and therefore should shield the spin density from the environment.... -
Revealing the Structure behind the Synergistic Phase Behavior of the Ternary ...
The aim of this collaborative proposal is to unravel micro- and nano-structures underlying unusually high solution viscosities from mixed surfactant systems. SANS is a unique... -
Electrolyte induced self-assembly of methyl ester sulphonate surfactants
The addition of multivalent counterions (Al3+, Mg2+) induces multilayer adsorption of ionic surfactants at interfaces. It is associated with strong wetting conditions, invoking... -
Molecular interactions between phospholipid monolayers and dimethylsulphoxide
Neutron reflectivity will be employed to investigate the interaction between dimethylsulphoxide and monomolecular films of phosphatidylcholine. The monolayer will be used as a... -
Adsorption kinetics from polymer/surfactant systems; PSS/CnTAB
Polymer-surfactant mixtures are widely used in commercial formulations in personal care, pharmaceutical and agrochemical, cleaning, automotive and food industries. The... -
Adsorption of Organic Phosphate onto Silicon
This proposal presents to directly measure ¿bridging¿ of anionic surfactants on an anionic surface through multivalent ions from water under well-controlled conditions (pHs and... -
Conformational changes on interaction of cytochrome c with lipid monolayers.
The main objective of the present work is to gain an understanding of the interaction of the cationic protein, cyt c with anionic lipid membranes. This objective will be... -
SANS Study of the interaction of model wax alcohols with non-ionic surfactant...
The understanding of the plant wax-surfactant interaction process is crucial to the development of more effective pesticide and fungicide formulations, essential for improving... -
Insertion of antimicrobial peptides into phospholipid monolayers at air/liqui...
We have designed a series of cationic peptides with different helix repeats that can kill bacteria but remain benign to mammalian host cells. The selectivity to cell types is... -
Solution Aggregation of Short Peptide Amphiphiles
Short peptide sequences consisting of hydrophobic and hydrophilic amino acid units are capable of self-assembly, leading interfacial adsorption and solution nano-aggregation....