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Single Domain pH-Driven DNA Nanoswitch
DNA is an extremely versatile building material for the development and assembly of functional nanostructures and nanodevices. There are numerous examples of DNA based... -
Proving ground-state ordering in Artificial Spin-Ice systems formed by sub-10...
The main purpose of the experiment proposed here is to study the effects of thermalisation on Artificial Spin-Ice (ASI) systems formed by nanomagnets with sub-100 nm lateral... -
Surface activity of fluoroblock copolymers in model marine coatings
Marine coatings are commonly based on silicone polymers, which have a low surface energy and a degree of deformability which contribute to release of marine fouling species. Low... -
Proving ground-state ordering in Artificial Spin-Ice systems formed by sub-10...
The main purpose of the experiment proposed here is to study the effects of thermalisation on Artificial Spin-Ice (ASI) systems formed by nanomagnets with sub-100 nm lateral... -
Application of direct inversion to magnetic contrast datasets.
We have developed an experimental approach using a buried magnetic layer to provide contrast in systems consisting of complex biomolecular layers tethered to gold surfaces. This... -
Neutron Reflection from a Biomineralisation Glycosaminoglycan on Calcite
Here we aim to structurally characterise the formation of adsorbed monolayers of heparin on calcite to address how these species influence biomineralisation and the inhibition... -
Microstructure of Homoeopathic Organic Solar Cells
Much progress has been made researching organic solar cells (OSC) in the last two decades, but the field still holds surprises. Until recently, the general assumption was that... -
Bilayer lipid membranes tethered by commercial surfactants on electrochemical...
Phospholipids assemble the backbone of biological membranes and their simplified biomimetic models, in particular sparsely tethered bilayer membranes (stBLM) were established to... -
INTERACTIONS OF PAMAM DENDRIMERS WITH DESIGNER BIOSURFACTANTS AT THE SOLID/LI...
Poly(amidoamine) (PAMAM) dendrimers have been identified as potential gene vectors. We have studied their association with surfactants, dilauroylphospholiponucleosides (DLPN),... -
Surfactants at the metal-oil interface
The lubrication of surfaces by oils is a key aspect of many academic and industrial problems with significant financial implications. In this experiment we would like to extend... -
Quasi-elastic neutron scattering using Neutron Spin echo
We propose a measurement of the effectiveness of using the RF flippers on Offspec in a quasi-elastic mode (theta=90°) with the RF at 0.5MHz. This is important to our future... -
A comparative NR study of interaction of short designed antimicrobial peptide...
The global increase of bacterial resistance to antibiotics has led to increasing interest in research focusing on the development and characterization of new antimicrobial... -
Self-assembling antimicrobial peptides: interactions with model lipid membranes
We propose to investigate antimicrobial peptides that self-assemble into well-defined nanostructures. Previous SAXS results have shown that the peptides form rather robust... -
Substrate-dependent structure of thin hydrogel films
Hydrogels are water-rich polymer networks made from natural or synthetic polymers, which are widely used in biomaterials, medicine and antifouling. We have developed PEG-based... -
Controlling the morphology of fullerene-free polymer solar cells using additi...
We have recently demonstrated, using neutron reflectivity in combination with other techniques, that in organic photovoltaic devices (OPVs) the additive 1,8-diiodooctane (DIO)... -
Polarised neutron investigations of the spin Seebeck effect
The spin Seebeck effect generates spin currents in various materials when they are subjected to a temperature gradient. These spin currents persist over length scales many... -
Ageing Effects in Polymer Surfactant Films
We have recently reported a remarkably rich range of surface segregation and self-organisation behaviour for surfactants and plasticisers in PVA film. These experiments are... -
Modelling the Intracellular Lipid Shuttling Mechanism of Non Specific Lipid T...
Previously we have examined the interaction of barley non-specific lipid transfer protein (nsLTP1) with OTS and lipid monolayers at the solid/liquid interface. Examining the... -
Magnetic contrast NR to resolve MscL opening under PXG challenge
In bacteria, mechanosensitive ion channels such as MscL protect cells against osmotic shock, but, as with all ion channels, they have the potential to act as an Achilles heel,... -
Magnetic contrast reflectometry to resolve transmembrane potential effects on...
The division of bacteria is controlled by the binding of proteins to the inner of the two lipid bilayer membranes that separates the inside of the cell from the outside world....