115 datasets found

We have previously shown that peptides such as G(IIKK)4I-NH2 (G4) can kill bacteria and inhibit cancer cell growth whilst remaining benign to mammalian host cells. We have also...

Bacterial and fungal infections of cereal crops pose considerable risk to food security. Pathogenic resistance to conventional fungicides and pesticides is becoming widespread...

This proposal presents to directly measure ¿bridging¿ of anionic surfactants on an anionic surface through multivalent ions from water under well-controlled conditions (pHs and...

We will add temperature control to our reaction chamber for simultaneous neutron reflectometry(NR) and infra-red reflection absorption spectroscopy (IRRAS). This new set-up will...

Liquid crystals (LCs) are known to act as good lubricants, however, the reason for this remains unclear. One contributing factor is thought to be the formation of ordered layers...

In the present proposal neutron reflectivity will be used in combination with contrast variation to detect changes in the presence (and size) of microdomains in monolayer films...

We have recently been able to form a thin graphene oxide (GO) film with uniform thickness around 30±2Å from aqueous GO suspensions by spin coating (onto small wafers for...

Sulfobetaines are zwitterionic surfactants where the headgroup charges are arranged in the opposite manner to those found in phosphotidylcholine lipid headgroups. Sulfobetaines...

Gold provides a high quality surface on which to arrange biomolecules such as proteins since we can use cysteine amino acids to deliver gold thiol chemical bonds which can...

We ask for 3 days of beam time on Inter/SURF to study the adsorption and adlayer characteristics of avidin on Ti surfaces, relevant for biomedical applications, such as...

Antibody-antigen binding has been extensively used in many technological applications such as immunoassays, chemical analysis and bionanotechnology. The crucial element...

Many drugs are both poorly water-soluble (hydrophobic) and lipophilic in nature and are therefore incorporated into surfactant micelles and monolayers. As the incorporation of...

The gram-negative bacterial membrane is of extreme medical importance. The two main lipid components of the outer membrane are lipopolysaccharides (LPS's) and DOPE. We will...

In a recent experiment carried out on SURF we have shown that on addition of ethanol to a DPPC model membrane, the anaesthetic initially diffuses to the bilayer surface followed...

The proposal is to use previous established neutron reflection methods to observe the smectic layers that form at the surface of a nematic liquid crystal. In this proposal we...

Poly(amidoamine) (PAMAM) dendrimers have been identified as potential gene vectors. We have studied their association with surfactants, dilauroylphospholiponucleosides (DLPN),...

Mixed films of palmitic acid (PA) and galactocerebrosides (GCB) –a proxy for marine aerosol– exhibit attractive interactions due to H-bonding of galactose and carbonyl head...

The adsorption of a liquid crystal dopant to a surface can have a significant impact on its properties such as electro-optic response and lubrication. Both the interesting...

Bacterial and fungal infections of cereal crops pose a considerable risk to global food security. Typically plant pathogens are controlled through the use of chemical agents...

Our objective is to create asymmetric solid surface tethered bilayers (tBLMs) with the the outer leaflet predominately populated by charged phospholipids. tBLMs are produced by...