82 datasets found

Pluronic micelles are attractive candidates as drug carriers. Despite the abundance of data on their association with various drugs, there is, in contrast, very little...

This proposal aims to explore a cheaper and more environmental-benign surfactant system for yielding efficient water/CO2 microemulsions. The new surfactants permit high...

Many formulations comprise distinct chemical species that exhibit antagonistic or synergistic interactions that result in unpredictable behaviour. Previous work from our group...

Assembly of the peptidoglycan later of bacterial cell walls is a validated target for anti-bacterial agents: the late transpeptidation and transglycosylation steps are inhibited...

Gene (nucleic acid) delivery to the cytosol or nucleus of a cell is, without the aid of a suitable delivery system, an inefficient process. Here the interaction of a defined...

Amine-functionalised poly(alkylene oxides) are used extensively as swelling inhibitors in water-based drilling fluids. This study will broaden our understanding of the mechanism...

The project is to understand fundamental structure-performance relationships of chemical demulsifiers in water-in-crude oil (w/o) systems. In particular, to understand how...

There is conflicting information about properties of polycrylic acid and its behaviour in aqueous solution. This proposal for an investigation by SANS that is directed at...

Conjugation of therapeutic proteins to polymers is well established but most methods result in multi-site and multiple conjugation, crosslinking resulting in lack of orientation...

The aim of the study is to use SANS in combination with contrast variation to determine the effect of solubilising the lipophilic drug, testosterone propionate, in micelles...

This proposal aims to explore aqueous phase structures and compositions of a series of mixed surfactants. Although standard surfactant mixtures have been extensively studied...

Deep Eutectic Solvents (DES) are molecular mixtures similar to ionic liquids, having melting points below room temperature. DES share many of the features of ionic liquids (low...

One dimensional (1D) magnetic nanostructures exhibit anisotropic magnetic properties and thereby differ from unstructured materials. However, magnetic chains are energetically...

Our group has been working functionalised cellulose nanofibrils which form gels in aqueous formulations. Previously we have used these fibrils to stabilise oil-in-water...

Liposomes are lipid-based, water-filled vesicles with wide-ranging applications in diagnostics and drug delivery. Phospholipases (PLs) are enzymes that cleave specific bonds in...

For biomaterial applications, it is important that the properties of self-assembled hydrogels are well controlled and match the requirements of the application. The influence of...

It is proposed that radioactive waste generated in the Netherlands be buried underground in Boom clay formations. As this will need to be stored for hundreds of thousands of...

Our group has been working partially oxidized cellulose nanofibrils which form gels in aqueous formulations. Recently we have observed that these fibrils also gel when dialysed...

The aim of the experiment is to employ SANS to study the physical properties of a novel and very stable aqueous Fe3O4 ferrofluid system stabilized by the commercially available...

Short peptide sequences consisting of hydrophobic and hydrophilic amino acid units are capable of self-assembly to lead to interfacial adsorption and solution nano-aggregation....