SAXS studies of radiation damages induced in protein complexes with Cu(II) and Zn(II) cations

DOI

The aim of this research project is to determine the influence of synchrotron radiation on the induction of radiation damage in selected model protein structures in the presence of copper, zinc and other divalent metal ions. Human serum albumin (HSA) and human cystatin C (HCC) were selected as model systems, which were previously examined using X-ray absorption spectroscopy (XAS) in complexes mainly with Cu(II) and Zn(II) cations. The analysis using the bioSAXS technique will determine potential structural changes and correlates them with radiation damages visible in XAS studies.

Identifier
DOI https://doi.org/10.15151/ESRF-ES-1443770770
Metadata Access https://icatplus.esrf.fr/oaipmh/request?verb=GetRecord&metadataPrefix=oai_datacite&identifier=oai:icatplus.esrf.fr:inv/1443770770
Provenance
Creator Ahmed S. A. MOHAMMED; Karolina RUCIŃSKA; Joanna MAKSIM; Maciej KOZAK ORCID logo; Mark TULLY ORCID logo
Publisher ESRF (European Synchrotron Radiation Facility)
Publication Year 2027
Rights CC-BY-4.0; https://creativecommons.org/licenses/by/4.0
OpenAccess true
Representation
Resource Type Data from large facility measurement; Collection
Discipline Particles, Nuclei and Fields