This data set comprises CTD data of the RV ALKOR cruise AL568b conducted in January 2022 (January 24th – February 1st) in the Western Baltic Sea by the University of Hamburg. The cruise was part of the 5-year monitoring programme Winter cod 2021-25 (Monitoring winter spawning activity of Western Baltic cod (Gadus morhua) (2021-25)) of the University of Hamburg aiming at investigating the early-winter spawning activity of Western Baltic cod to identify potential climate-induced shifts in spawning phenology.