Two-dimensional correlation analysis of IINS of water with amino acids.

DOI

The interaction of water with biomolecules is of significant interest. To analyse the spectra, we are employing 2D correlation analysis. This has been used extensively with infrared and Raman spectra, but this is the first time for INS data. The software is able to give band assignments and can also identify interaction mechanisms, further still it can give an indication to the sequence in which these interactions occur. The combination of this technique with computer simulations allows insight into the vibrational modes and dynamics present in amino acids with the introduction of water. To continue this study and further investigate these interactions, 3 amino acids have been chosen to be studied, each requiring a minimum of 4 spectra each. We would like to apply for 3 days on TOSCA to record a total of 12 spectra.

Identifier
DOI https://doi.org/10.5286/ISIS.E.24032945
Metadata Access https://icatisis.esc.rl.ac.uk/oaipmh/request?verb=GetRecord&metadataPrefix=oai_datacite&identifier=oai:icatisis.esc.rl.ac.uk:inv/24032945
Provenance
Creator Dr Anibal Ramirez-Cuesta; Miss Kay Chan; Professor Bob Ford
Publisher ISIS Neutron and Muon Source
Publication Year 2012
Rights CC-BY Attribution 4.0 International; https://creativecommons.org/licenses/by/4.0/
OpenAccess true
Contact isisdata(at)stfc.ac.uk
Representation
Resource Type Dataset
Discipline Photon- and Neutron Geosciences
Temporal Coverage Begin 2008-12-07T10:04:45Z
Temporal Coverage End 2009-05-31T05:45:00Z