The
data repository consists of four files of summary statistics from the two-cohort (Cambridge and
EUGENDA) GWAS meta-analyses of FH and FHR-4 levels: METAANALYSIS_FH_ALL-adjAMD.txt (tab-separated values file; size: 448Mb)METAANALYSIS_FH_controls.txt (tab-separated values file; size: 448Mb)
METAANALYSIS_FHR4_ALL-adjAMD.txt (tab-separated values file; size: 432Mb)
METAANALYSIS_FHR4_controls.txt (tab-separated values file; size: 432Mb)The single-cohort GWASs were
carried out using EPACTS software available at http://genome.sph.umich.edu/wiki/EPACTS; effect size estimates and standard errors of single variants seen in
both cohorts were subsequently combined in a fixed-effect meta-analysis using
METAL software
available at http://csg.sph.umich.edu/abecasis/metal/download/.More details are provided in the Readme.pdf file.