The datasets contains foraminiferal oxygen isotope (δ¹⁸O) records of MD10-3340, retrieved in the Halmahera Sea. The records of G. ruber (250 to 350 µm) and P. obliquiloculata (350 to 440 µm) were measured at the State Key Laboratory of Marine Geology, Tongji University, Shanghai, China with a Finnigan-MAT253 mass spectrometer. Conversion to the international Pee Dee belemnite scale was performed using NBS19 standard, and the long-term variability of δ¹⁸O is better than 0.07 per mil. The records cover the last ~235 ka.