Duplex stainless steels have an attractive combination of high strength and corrosion resistance, making them the natural choice in applications such as e.g. pressurised equipment in the nuclear-, chemical- and pulp & paper industry. Increased efficiency in these applications is linked to higher service temperatures, but the service temperature of duplex stainless steels is limited to ~250°C. This is due to the decomposition (embrittlement) of the alloy and subsequent degradation of its mechanical properties. Hence, it is the purpose of the present project to develop a holistic methodology for the design of novel duplex stainless steels that are less sensitive to low-temperature embrittlement. This will be achieved by combining of state-of-the-art multi-scale computational models and advanced experimental analysis using SANS, APT and TEM.