Nowadays, Fe3O4 iron oxide nanoparticles (Fe3O4 MNPs) have attracted attention as highly performing contrast agents for Magnetic Resonance Imaging technique (MRI), aiming to early detection of several pathologies, such as cancer [1]. However, some concerns about the biocompatibility are limiting their use in the biomedical field. Thus, we implemented a novel functionalization strategy, based on the use of phospholipids, known biocompatible molecules. The structure and the packing degree of the nanoparticle organic coating represent a fundamental variable in the development of biocompatible devices. Thus, we propose to characterize the functionalized Fe3O4 MNPs, focusing on the organization of the organic coating, performing elastic and quasi-elastic neutron scattering, as well as small angle neutron scattering, experiments.