In this work we present a continuous record of quantitative estimations of eastern-western E-W Med water exchange since the last deglaciation, including the YD and the S1 events. Estimations are based on neodymium isotope (εNd) measurements on planktic foraminifera Fe-Mn crusts. We use a sediment core NDT-6-2016 collected during the Next Data expedition (CNR-URANIA R/V, Date/Time : 2016-06-25T05:19:44) in the transition area between the W-Sicily channel and the southern Tyrrhenian Sea (38°0'26,60'' N and 11°47'44,84''E) at 1066 m of water depth. The core depth is below the present-day interphase between WMDW and the EMSW outflowing through the Strait of Sicily, thus a suitable location to evaluate changes in the intermediate-deep water exchange between the two main Mediterranean sub-basins.