A Time-Resolved SANS Study of the Gelation Mechanisms of Tetrapeptide Hydrogelators

DOI

Time-resolved SANS will be used to investigate the mechanisms and kinetics of ordering of aseries of novel designed tetrapeptide-based hydrogelators. These inexpensive materials arebiocompatible and biofunctional and may find applications in medicine. Peptide hydrogels have been the subject of many studies using TEM and SEM but there are very few neutron scattering studies focussed on the mechanisms of aggregation. TEM shows that several of the tetrapeptide hydrogelators self-assemble into fibrils. The kinetics and mechanisms of this process, and its dependence on preparationconditions, will be examined by SANS.

Identifier
DOI https://doi.org/10.5286/ISIS.E.24089941
Metadata Access https://icatisis.esc.rl.ac.uk/oaipmh/request?verb=GetRecord&metadataPrefix=oai_datacite&identifier=oai:icatisis.esc.rl.ac.uk:inv/24089941
Provenance
Creator Professor Ian Hamley; Dr Valeria Castelletto; Dr Wayne Hayes; Ms Marta Tena-Solsona; Mr Ashkan Dehsorkhi
Publisher ISIS Neutron and Muon Source
Publication Year 2015
Rights CC-BY Attribution 4.0 International; https://creativecommons.org/licenses/by/4.0/
OpenAccess true
Contact isisdata(at)stfc.ac.uk
Representation
Resource Type Dataset
Discipline Photon- and Neutron Geosciences
Temporal Coverage Begin 2012-12-11T09:10:40Z
Temporal Coverage End 2012-12-14T03:42:44Z